Sunday, January 11, 2009

37 - pharmacology mcqs - 58 to 68


58q. digoxin is contraindicated in ?

a. SVT
b. AF
c. CHF
d. HOCM

answer: d . HOCM - hypertrophic obstructive cardiomyopathy .

59q. digoxin is not indicated in ?

a. atrial flutter
b. atrial fibrillation
c. high output failure
d. PSVT

answer: c . high output failure .

60q. which of the following drugs is a topoisomerase 1 inhibitor ?

a. doxorubicin
b. irinotecan
c. etoposide
d. vincristine

answer: b . irinotecan . topotecan and irinotecan are campothecin analogues .

61q. the treatment of contacts of meningococcal meningitis ?

a. rifampicin
b. erythromycin
c. pencillin
d. cephalosporins 

answer: a . rifampicin .

62q. SLE like syndrome is most commonly associated with the administration of the following drug ?

a. rifampicin
b. procainamide
c. digitalis
d. phenytoin

answer: b . procainamide .

63q. cyclosporine acts by inhibiting the production of ?

a. IL 1
b. IL 2
c. IL 3
d. macrophages

answer: b . IL 2 .

64q. drugs avoided in G6PD deficiency ?

a. chloramphenicol
b. quinidine
c. nitrofurantoin
d. dapsone
e. streptomycin 


65q. volume of  distribution of drugs is altered in ?

a. obesity
b. athletes
c. pregnancy
d. older age 
e. neonate

answer: a,c,d,e. all except athletes .

66q. the drug of choice to treat severe hypertension due to acute nephritis in children is ?

a. propranolol
b. reserpine
c. frusemide
d. nifedipine

answer: d . nifedipine .

67q. digoxin is eliminated from the body by ?

a. tubular filtration
b. hepatic conjugation
c. glomerular filtration
d. oxidation

answer: c . glomerular filtration .

68q. drug of choice in prinzmetal's angina ?

answer: diltiazem .

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