| Inhibitors of nucleic acid synthesis | Quinolones | DNA gyrase | Bactericidal |
| Novobiocin | DNA gyrase | Bacteriostatic | |
| Flucytosine | Fungal thymidylate synthetase | Fungicidal | |
| Rifampin | DNA-dependent RNA polymerase | Bactericidal | |
| Inhibitors of folate metabolism | Sulfonamides | Pteroic acid synthetase | Bacteriostatic |
| Trimethoprim | Dihydrofolate reductase | Bacteriostatic | |
| Inhibitor of mycolic acid synthesis | Isoniazid | Mycobacterial mycolic acid biosynthesis | Bactericidal |
| Alteration of cytoplasmic membrane | Polymyxins | Bacterial membrane permeability | Bactericidal |
| Polyenes | Fungal membrane permeability | Fungicidal | |
| Azoles | Fungal ergosterol biosynthesis | Fungicidal |
Friday, September 11, 2009
51 - Antimicrobial chemotherapy - Rest of drugs
50 - Antimicrobial chemotherapy - Protein biosynthesis inhibitors
| Streptomycin | 30S ribosomal subunit | Bactericidal |
| Gentamicin | 30S ribosomal subunit | Bactericidal |
| Tetracycline | 30S ribosomal subunit | Bacteriostatic |
| Spectinomycin | 30S ribosomal subunit | Bacteriostatic |
| Chloramphenicol | 50S ribosomal subunit | Bacteriostatic |
| Erythromycin | 50S ribosomal subunit | Bacteriostatic |
| Clindamycin | 50S ribosomal subunit | Bacteriostatic |
| Griseofulvin | Microtubule function | Fungistatic |
49 - Antimicrobial chemotherapy - Cell wall synthesis inhibitors
| | AGENT Cycloserine | SITE OF ACTION Peptidoglycan tetrapeptide side chain | EFFECT Bactericidal | |
Phosphomycin | Formation of N-acetylmuramic acid | Bactericidal | ||
Bacitracin | Membrane carrier molecule | Bactericidal | ||
Penicillins | Peptidoglycan cross-linking | Bactericidal | ||
Cephalosporins carbapenems | , Peptidoglycan cross-linking | Bactericidal | ||
Vancomycin | Translocation of cell wall intermediates | Bactericidal |
48 - Atypical Antipsychotic drugs
Atypical antipsychotics are those drugs which act as antipsychotics but atypically have a very low risk of producing adverse extrapyramidal neurological side effects . These are
1. Risperidone
2. Quetiapine
3. Arisipiprazole
4. Clozapine
5. Olanzapine
6. Ziprasodine
Click here to read the mnemonic used to remember these drugs .
1. Risperidone
2. Quetiapine
3. Arisipiprazole
4. Clozapine
5. Olanzapine
6. Ziprasodine
Click here to read the mnemonic used to remember these drugs .
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