Friday, September 11, 2009

49 - Antimicrobial chemotherapy - Cell wall synthesis inhibitors

             
 
 AGENT

Cycloserine
     SITE OF ACTION


     Peptidoglycan tetrapeptide side chain
    EFFECT

    Bactericidal

Phosphomycin

     Formation of N-acetylmuramic acid

    Bactericidal

Bacitracin

     Membrane carrier molecule

    Bactericidal

Penicillins

     Peptidoglycan cross-linking

    Bactericidal

Cephalosporins
carbapenems

,     Peptidoglycan cross-linking

    Bactericidal

Vancomycin

     Translocation of cell wall   intermediates

    Bactericidal



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