Friday, September 11, 2009

49 - Antimicrobial chemotherapy - Cell wall synthesis inhibitors

             
 
 AGENT

Cycloserine
     SITE OF ACTION


     Peptidoglycan tetrapeptide side chain
    EFFECT

    Bactericidal

Phosphomycin

     Formation of N-acetylmuramic acid

    Bactericidal

Bacitracin

     Membrane carrier molecule

    Bactericidal

Penicillins

     Peptidoglycan cross-linking

    Bactericidal

Cephalosporins
carbapenems

,     Peptidoglycan cross-linking

    Bactericidal

Vancomycin

     Translocation of cell wall   intermediates

    Bactericidal



48 - Atypical Antipsychotic drugs

Atypical antipsychotics are those drugs which act as antipsychotics but atypically have a very low risk of producing adverse extrapyramidal neurological side effects . These are

1. Risperidone

2. Quetiapine

3. Arisipiprazole

4. Clozapine

5. Olanzapine

6. Ziprasodine

Click here to read the mnemonic used to remember these drugs .

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