53 - Benzodiazepine interactions with other drugs

Benzodiazepine interactions with other drugs.

Drug Effects Antacids Decreased absorption of benzodiazepines Cimetidine Increased half-life of diazepam and  triazolam Contraceptives Increased levels of diazepam and  triazolam Digoxin Alprazolam and diazepam raise  digoxin level Disulfiram Increased duration of action of sedatives Isoniazid Increased plasma diazepam Levodopa Inhibition of antiparkinsonism effect Propoxyphene Impaired clearance of diazepam Rifampin Decreased plasma diazepam Warfarin Decreased prothrombin time