There are mainly four type of hypolipidemic drugs , they are
- statins : they act by inhibiting the enzyme HMG CoA reductase which is the rate limiting step of cholesterol synthesis .
examples of statins are : lovastatin, mevastatin, simvastatin , rosuvastatin .
- fibric acid derivatives : these drugs act by activating the lipoprotein lipase .
examples are : gemfibrozil , clofibrate .
- bile acid resins : these drugs act by interrupting the enterohepatic recycling of bile acids .
examples of bile acid resins are : cholestyramine and cholestipol .
- nicotinic acid : this drug acts by unclear mechanisms but it is believed that it acts by inhibition of lipolysis .
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