Friday, September 11, 2009

51 - Antimicrobial chemotherapy - Rest of drugs

Inhibitors of nucleic acid synthesisQuinolonesDNA gyraseBactericidal
NovobiocinDNA gyraseBacteriostatic
FlucytosineFungal thymidylate synthetaseFungicidal
RifampinDNA-dependent RNA polymeraseBactericidal


Inhibitors of folate metabolismSulfonamidesPteroic acid synthetaseBacteriostatic
TrimethoprimDihydrofolate reductaseBacteriostatic


Inhibitor of mycolic acid synthesisIsoniazidMycobacterial mycolic acid biosynthesisBactericidal


Alteration of cytoplasmic membranePolymyxinsBacterial membrane permeabilityBactericidal
PolyenesFungal membrane permeabilityFungicidal
AzolesFungal ergosterol biosynthesisFungicidal


50 - Antimicrobial chemotherapy - Protein biosynthesis inhibitors

Streptomycin     30S ribosomal subunitBactericidal
Gentamicin     30S ribosomal subunit               
Bactericidal
Tetracycline     30S ribosomal subunitBacteriostatic
Spectinomycin     30S ribosomal subunitBacteriostatic
Chloramphenicol     50S ribosomal subunitBacteriostatic
Erythromycin     50S ribosomal subunitBacteriostatic
Clindamycin     50S ribosomal subunitBacteriostatic
Griseofulvin     Microtubule functionFungistatic


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